Reaktion #3708

Reaktionsgleichung

3-methoxy-4-nitrobenzoic acid

thionyl chloride

→

3-Methoxy-4-nitrobenzoyl chloride

Lösungsmittel

iso-octane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis heated
2. 2
   Temperaturto reflux for 2 hours
3. 3
   Sonstigethe mixture evaporated in vacuo to a solid residue
4. 4
   WaschenThe residue is washed with iso-octane (2×2 ml)
5. 5
   Sonstigedried in vacuo
6. 6
   Sonstigeto give 1.08 g of cream

Vorschrift

A stirred suspension of 1.0 g of 3-methoxy-4-nitrobenzoic acid and 1.40 ml of thionyl chloride is heated to reflux for 2 hours. The mixture is cooled to room temperature, 2 ml of iso-octane added and the mixture evaporated in vacuo to a solid residue. The residue is washed with iso-octane (2×2 ml), dried in vacuo to give 1.08 g of cream colored solid.

Quelle