Reaktion #367738

Reaktionsgleichung

5,6-dimethoxysaccharin

triethyloxonium tetrafluoroborate

→

title compound

5,6-Dimethoxy-3-ethoxy-benzoisothiazole-1,1-dioxide

Lösungsmittel

dichloromethane

CH2Cl2

Reaktionsbedingungen

Aufarbeitung

1. 1
   ExtraktionAfter extraction with aqueous sodium bicarbonate
2. 2
   Sonstigethe organic phase was dried
3. 3
   Einengenconcentrated
4. 4
   SonstigePurification by column chromatography (silica, chloroform)

Vorschrift

To a solution of 5,6-dimethoxysaccharin (0.8 g) in dichloromethane (100 ml) was added triethyloxonium tetrafluoroborate (3.5 ml, 1M soln in CH2Cl2) and the solution stirred at room temperature for 3 hrs. After extraction with aqueous sodium bicarbonate, the organic phase was dried and concentrated. Purification by column chromatography (silica, chloroform) gave the title compound (0.2 g).

Quelle