Reaktion #367574

Reaktionsgleichung

tetrahydrofuran

butane-1,4-diol

→

butane-1,4-diol

acetylene

formaldehyde

but-2-yne-1,4-diol

Lösungsmittel

water

Reaktionsbedingungen

Vorschrift

We have found that this object is achieved by a novel process in which tetrahydrofuran is prepared from an aqueous butane-1,4-diol solution by eliminating water in the aqueous phase at elevated temperatures, under superatmospheric pressure and in the presence of an acid, wherein a crude aqueous solution of butane-1,4-diol, obtained by reaction of acetylene with aqueous formaldehyde and catalytic hydrogenation of the resulting but-2-yne-1,4-diol solution, is, when starting with a crude alkaline aqueous solution, neutralized with sulfuric acid, acidified by adding phosphoric acid, and then heated at from 200° to 260° C. under superatmospheric pressure.

Quelle