Reaktion #367496

Reaktionsgleichung

3-chlorophenylglyoxal

2-(4-Methylphenyl)-1,1-dimethyl ethanamine

→

title compound

N-(2-(4-Methylphenyl)-1,1-dimethylethyl)-2-hydroxy-2-(3-chlorophenyl)ethanamine

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe title compound was prepared in the manner
2. 2
   SonstigeThe chromatographed material was recrystallized from cyclohexane

Vorschrift

The title compound was prepared in the manner described in Example 9 using 3-chlorophenylglyoxal and 2-(4-Methylphenyl)-1,1-dimethyl ethanamine. The chromatographed material was recrystallized from cyclohexane to give the title compound m.p. 104-105. τ(CDCL3), 8.9 (6H, s), 7.7 (3H, s), 7.4 (2H, s), 7.1 (2H, dd,), 5.45 (1H, dd), 3.0 (4H, s), 2.5-2.8 (4H, m).

Quelle