Reaktion #365385

Reaktionsgleichung

4-phenylbutyl bromide

triphenylphosphine

→

title compound

(4-Phenylbut-1-yl)triphenylphosphonium bromide

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe solid precipitate was collected by filtration
2. 2
   Waschenwashed with toluene and air
3. 3
   Sonstigedried
4. 4
   workup.DISSOLUTIONThe solid was dissolved in a 2:1 mixture of water and acetonitrile

Vorschrift

A solution of 4-phenylbutyl bromide from the Step A (24.7 g) and triphenylphosphine (19.00 g) in toluene (100 mL) was heated at 120-130° C. for 3 days. The reaction was cooled to rt and the solid precipitate was collected by filtration, washed with toluene and air dried. The solid was dissolved in a 2:1 mixture of water and acetonitrile and gave the title compound (30.6 g) as a white solid after lyopholization.

Quelle