Reaktion #363858

ord-a3321bbe513340c99efa429a99565c33

Reaktionsgleichung

Cc1cc([N+](=O)[O-])ccc1N=C=S
2-Methyl-4-nitrophenyl isothiocyanate
C[C@H](N)C1CCCCC1
(1S)-1-amino-1-cyclohexylethane
CC(Cl)C(=O)O
α-chloropropionic acid
→
Cc1cc([N+](=O)[O-])ccc1N=C1SC(C)C(=O)N1[C@@H](C)C1CCCCC1
2-(2-methyl-4-nitrophenylimino)-3-((1S)-1-cyclohexylethyl)-5-methyl-1,3-thiazolidin4-one

Edukte

Cc1cc([N+](=O)[O-])ccc1N=C=S
2-Methyl-4-nitrophenyl isothiocyanate
C[C@H](N)C1CCCCC1
(1S)-1-amino-1-cyclohexylethane
CC(Cl)C(=O)O
α-chloropropionic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2-Methyl-4-nitrophenyl isothiocyanate was reacted with (1S)-1-amino-1-cyclohexylethane followed by α-chloropropionic acid according to Method C8a to afford 2-(2-methyl-4-nitrophenylimino)-3-((1S)-1-cyclohexylethyl)-5-methyl-1,3-thiazolidin4-one.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06353006B1uspto-grants-2002_03