Reaktion #363674
ord-8e3bbff1cfb14735b2fe03e17f2fd2f1
Reaktionsgleichung
(1S)-1-Isopropyl-2-hydroxyethylamine
SOCl2
2-methyl-4-nitrophenyl isothiocyanate
→
(4S)-2-(2-methyl-4-nitrophenylimino)-4-isopropyl-1,3-thiazolidine
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
(1S)-1-Isopropyl-2-hydroxyethylamine was reacted with SOCl2 followed by 2-methyl-4-nitrophenyl isothiocyanate according to Method C2a to give (4S)-2-(2-methyl-4-nitrophenylimino)-4-isopropyl-1,3-thiazolidine. The thiazolidine was reacted with cyclopentyl bromide according to Method D2a to afford (4S)-2-(2-methyl-4-nitrophenylimino)-4-isopropyl-3-cyclopentyl-1,3-thiazolidine.