Reaktion #363347

Reaktionsgleichung

benzaldehyde

2-amino-3-picoline

aniline

bezoic acid

1-hexene

toluene

→

heptanophenone

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.STIRRINGthe reactants were stirred at various temperatures (70-130° C.)
2. 2
   workup.WAITas shown in the following table 10 for 1 hour
3. 3
   SonstigeAfter completion of the reaction, gas chromatography

Vorschrift

Under the same reaction procedure and conditions as in Example 1 (benzaldehyde 0.5 mmol, 2-amino-3-picoline 0.1mmol, aniline 0.3 mmol, bezoic acid 0.03 mmol, 1-hexene 2.5 mmol, toluene 0.87 mmol), the mixture in a 500 ml pressure reactor was stirred at normal temperature for 2-3 minutes and then combined with Rh(PPh3)3Cl 1 0.01 mmol. While the reactor was stopped with a stopper, the reactants were stirred at various temperatures (70-130° C.) as shown in the following table 10 for 1 hour. After completion of the reaction, gas chromatography was conducted to determine the yields of heptanophenone, products according to various temperatures and the results are given in Table 10, below.

Quelle