Reaktion #363346

Reaktionsgleichung

benzaldehyde

2-amino-3-picoline

aniline

bezoic acid

1-hexene

toluene

→

heptanophenone

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.STIRRINGthe reactants were stirred at 130 ° C. for various reaction times
2. 2
   SonstigeAfter completion of the reaction, gas chromatography

Vorschrift

Under the same reaction procedure and conditions as in Example 1 (benzaldehyde 0.5 mmol, 2-amino-3-picoline 0.1 mmol, aniline 0.3 mmol, bezoic acid 0.03 mmol, 1-hexene 2.5 mmol, toluene 0.87 mmol), the mixture in a 500 ml pressure reactor was stirred at normal temperature for 2-3 minutes and then combined with Rh(PPh3)3Cl 0.01 mmol. While the reactor was stopped with a stopper, the reactants were stirred at 130 ° C. for various reaction times as shown in the following table 9. After completion of the reaction, gas chromatography was conducted to determine the yields of heptanophenone, products according to various period of times and the results are given in Table 9, below.

Quelle