Reaktion #362822

Reaktionsgleichung

methyl lactate

behenyl alcohol

sodium hydride

→

Behenyl Lactate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigein a transesterification reaction
2. 2
   Sonstigepurged with nitrogen
3. 3
   Sonstigeinserted with overhead stirrer
4. 4
   SonstigeAt this temperature over 2 ml of methanol was collected
5. 5
   TemperaturThe contents were heated to 200° C. with a nitrogen sweep
6. 6
   Sonstigeto remove any volatile components
7. 7
   TemperaturAfter approximately 15 minutes at 200° C. the contents were cooled
8. 8
   TemperaturUpon cooling the product
9. 9
   Sonstigecrystallized

Vorschrift

Behenyl Lactate was prepared by reacting methyl lactate (Aldrich Chemical Company, Inc. of Milwaukee, Wis.) with Lanette 22 (behenyl alcohol, 90%, Henkel Corp. of Ambler, Pa.) in a transesterification reaction according to the following method: 0.2 g sodium hydride (60% in mineral oil) was added to 32.6 grams Lanette 22 at 70° C. in a 3-neck 250ml glass flask purged with nitrogen and inserted with overhead stirrer, Dean Stark trap, thermometer, and condenser. To this was slowly added 9.4 g of methyl lactate and the contents were slowly heated to 160° C. and held at that temperature for one hour. At this temperature over 2 ml of methanol was collected. The contents were heated to 200° C. with a nitrogen sweep to remove any volatile components. After approximately 15 minutes at 200° C. the contents were cooled. Upon cooling the product crystallized and had a melting point of approximately 57° C.

Quelle