Reaktion #362264

Reaktionsgleichung

xylene

6-(trifluoromethyl)-1,4-naphthoquinone

1,2-dibromobenzocyclobutene

→

2-(Trifluoromethyl-)-naphthacene-5,12-dione

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder reflux for 16 hours
2. 2
   TemperaturThe mixture is cooled
3. 3
   Filtrationthe precipitate is filtered off
4. 4
   Waschenwashed with xylene

Vorschrift

5.65 g (25 mmol) of 6-(trifluoromethyl)-1,4-naphthoquinone, 9.82 g (about 37 mmol) of 1,2-dibromobenzocyclobutene (contaminated with a little 2-bromo-1-iodobenocyclobutene) and 100 ml of xylene are kept under reflux for 16 hours, using a water separator. The mixture is cooled and the precipitate is filtered off and washed with xylene. Yield 5.82 g (71%); melting point 253°-254° C. The procedure in Examples 58 to 61 is analogous.

Quelle