Reaktion #361499

Reaktionsgleichung

N,N-diethylformamide

N-formylpiperidine

2-diethylaminomethyleneamino-6-chloropurine

2-piperidinomethyleneamino-6-chloropurine

→

2-amino-6-chloropurine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto yield

Vorschrift

The reaction is carried out in the same manner as in Example 2 except that N,N-diethylformamide or N-formylpiperidine is used in the place of N,N-dimethylformamide to yield, respectively, a crystal of 2-diethylaminomethyleneamino-6-chloropurine or 2-piperidinomethyleneamino-6-chloropurine as an intermediate for further synthesis. A further treatment is carried out in the same manner as in Example 2 on these crystals to yield a white crystal of 2-amino-6-chloropurine.

Quelle