Reaktion #357592

ord-33b9ce389a0c40a4b6139b13d3a6dbcc

Reaktionsgleichung

Fc1ccc(-c2csc3cc(OCCCCBr)ccc23)cc1
6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene
CNC
dimethylamine
CN(C)CCCCOc1ccc2c(-c3ccc(F)cc3)csc2c1
{4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-dimethyl-amine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

In analogy to example 3.1, 6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and dimethylamine were converted to yield {4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-dimethyl-amine as white semisolid, MS: 344 (MH+).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07449483B2uspto-grants-2008_11