Reaktion #3556

Reaktionsgleichung

6-(2,6-dibromo-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine

tert-butyl isocyanate

→

title compound

1-[2-Amino-6-(2,6-dibromo-phenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butyl-urea

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe product was purified by MPLC
2. 2
   Wascheneluting with a gradient of CHCl3 :EtOAc (1:1) to EtOAc
3. 3
   Sonstigeto afford the pure product

Vorschrift

The title compound was prepared from 0.25 g of 6-(2,6-dibromo-phenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine from Example 60 and 0.077 mL of tert-butyl isocyanate according to Example 2. The product was purified by MPLC eluting with a gradient of CHCl3 :EtOAc (1:1) to EtOAc to afford the pure product; mp >300° C. (dec).

Quelle