Reaktion #355541

ord-636c392b8760460ba86b5bcddea2e93d

Reaktionsgleichung

COc1ccc(C(=O)c2c(-c3ccccc3)oc3ccc(Cl)cc23)cc1
5-chloro-3-(4-methoxybenzoyl)-2-phenylbenzofuran
Cl.c1ccncc1
pyridine hydrochloride
→
O=C(c1ccc(O)cc1)c1c(-c2ccccc2)oc2ccc(Cl)cc12
5-chloro-3-(4-hydroxybenzoyl)-2-phenylbenzofuran

Edukte

COc1ccc(C(=O)c2c(-c3ccccc3)oc3ccc(Cl)cc23)cc1
5-chloro-3-(4-methoxybenzoyl)-2-phenylbenzofuran
Cl.c1ccncc1
pyridine hydrochloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Demethylation of 5-chloro-3-(4-methoxybenzoyl)-2-phenylbenzofuran with pyridine hydrochloride as described above gives 5-chloro-3-(4-hydroxybenzoyl)-2-phenylbenzofuran.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US03947470uspto-grants-1976_03