Reaktion #355115

Reaktionsgleichung

sodium phenoxide

2,3-dichloropyrazine

→

2-chloro-3-phenoxypyrazine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis refluxed 10-20 hours
2. 2
   ExtraktionThe cooled mixture is extracted with diethyl ether
3. 3
   Waschenwashed with cold 2N sodium hydroxide solution
4. 4
   Sonstigedried
5. 5
   Sonstigeevaporated

Vorschrift

A suspension of 0.1 mole of sodium phenoxide and 0.1 mole 2,3-dichloropyrazine is refluxed 10-20 hours. The cooled mixture is extracted with diethyl ether, washed with cold 2N sodium hydroxide solution, dried, and evaporated to give 2-chloro-3-phenoxypyrazine.

Quelle