Reaktion #355067

Reaktionsgleichung

adamantane carboxylic acid chloride

p-trifluoromethylaniline

triethylamine

→

N-(4-Trifluoromethylphenyl)-1-adamantanecarboxamide

Lösungsmittel

methylene chloride hexane

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeCrystallize the residue
2. 2
   Sonstigeobtained
3. 3
   Sonstigeto obtain the product of this Example, m.p. 189°-193°C.

Vorschrift

Subject 2.0 g. of adamantane carboxylic acid chloride 1.6 g. (10 mmoles) of p-trifluoromethylaniline and 5.0 ml. of triethylamine to the process of Example 11. Crystallize the residue obtained thereby from a mixture of methylene chloride-hexane to obtain the product of this Example, m.p. 189°-193°C.

Quelle