Reaktion #354713

ord-0889bf70fd72450d83615d1449a9f2ec

Reaktionsgleichung

COc1cccc(C=O)c1
3-methoxybenzaldehyde
CCOC(=O)CC(=O)C(=O)OCC
oxalacetic acid diethyl ester
CCOC(=O)CC(=N)C(=O)OCC
iminosuccinic acid diethyl ester
→
CCOC(=O)C1=C(C(=O)OCC)C(c2cccc(OC)c2)C(C(=O)OCC)=C(C(=O)OCC)N1
4-(3'-Methoxyphenyl)-1,4-dihydropyridine-2,3,5,6-tetracarboxylic acid tetraethyl ester

Edukte

COc1cccc(C=O)c1
3-methoxybenzaldehyde
CCOC(=O)CC(=O)C(=O)OCC
oxalacetic acid diethyl ester
CCOC(=O)CC(=N)C(=O)OCC
iminosuccinic acid diethyl ester

Reagenzien

Keine

Lösungsmittel

CCO
ethanol

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigeafter evaporation a yellow oil
  2. 2
    Sonstigeis obtained

Vorschrift

13.6 g of 3-methoxybenzaldehyde, 19 g of oxalacetic acid diethyl ester and 18.8 g of iminosuccinic acid diethyl ester in 50 ccs of ethanol are heated to the boil for several hours, and after evaporation a yellow oil is obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US03943140uspto-grants-1976_03