Reaktion #353082

Reaktionsgleichung

Compound 23-2

4- [2-(N,N-Diethylamino)ethyloxy]benzoic acid

chloroethylpyrrolidine·HCl

NaH

→

27-6

Methyl 4-(2-Pyrrolidinylethyloxy)benzoate

Lösungsmittel

DMF

Reaktionsbedingungen

Vorschrift

Compound 23-2 (2 g, 11.8 mmol) and chloroethylpyrrolidine·HCl (Aldrich) (1.8 g, 11.8 mmol) were treated with NaH (0.94 g, 23.6 mmol) in DMF (30 mL) as described for 27-1 to give 27-6 as a clear oil. Rf (10% MeOH/CHCl3 saturated with NH3) 0.4

Quelle