Reaktion #352943
ord-f0f81bb389e747fb984060e82ca15e3c
Reaktionsgleichung
ethyl 4-(4-bromophenyl)butanoate
ethyl (3-bromophenyl)acetate
ethyl 3-bromophenylacetate
Compound B
ethyl 3-bromophenylacetate
→
title compound
Ethyl 4-(3-bromophenyl)butanoate
Edukte
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
Employing the same general multistep preparation as for ethyl 4-(4-bromophenyl)butanoate (Compound 60 g (246 mmol) of ethyl (3-bromophenyl)acetate (Compound B) was converted into the title compound (oil) using 255 ml (255 mmol) of diisobutylaluminum hydride (DIBAL-H, 1M in hexane), 85.8 g (250 mmol) of (carbethoxymethylene)triphenylphosphorane and 1.7 g of 10% Pd/C.