Reaktion #352174

ord-3719a323598e489290719ed5001a64a6

Reaktionsgleichung

CCCN(CCC)C1COc2cccc(N)c2C1
3-Dipropylamino-5-aminochroman
[N-]=[N+]=[N-].[Na+]
sodium azide
→
CCCN(CCC)C1COc2cccc(N=[N+]=[N-])c2C1
title compound
CCCN(CCC)C1COc2cccc(N=[N+]=[N-])c2C1
3-Dipropylamino-5-azidochroman

Edukte

CCCN(CCC)C1COc2cccc(N)c2C1
3-Dipropylamino-5-aminochroman
[N-]=[N+]=[N-].[Na+]
sodium azide

Reagenzien

Keine

Lösungsmittel

O
water

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    workup.STIRRINGAfter stirring at 5° C. overnight the solution
  2. 2
    Sonstigepurified

Vorschrift

3-Dipropylamino-5-aminochroman (Example 14; 0.050 g, 0.20 mmol) was diazotized according to the procedure of Example 15. After stirring for 15 minutes, sodium azide (0.026 g, 0.4 mmol) in water (1.0 ml) was added. After stirring at 5° C. overnight the solution was worked-up and purified according to the procedure of Example 15 to give the title compound. Mp 167°-168° C. (oxalate).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05646309uspto-grants-1997_07