Reaktion #349698

Reaktionsgleichung

5-(3-pyridylmethyl)-2-methylthio-4-pyrimidone

3-(5-methyl-4-imidazolylmethylthio)propylamine

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title compound

2-[3-(5-Methyl-4-imidazolylmethylthio)propylamino]-5-(3-pyridylmethyl)-4-pyrimidone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis heated at 130°-135° for 7 hours
2. 2
   SonstigeThe cool mixture is triturated with hot water
3. 3
   workup.ADDITIONtreated with dilute ethanolic HCl

Vorschrift

An intimate mixture of 5-(3-pyridylmethyl)-2-methylthio-4-pyrimidone and 3-(5-methyl-4-imidazolylmethylthio)propylamine is heated at 130°-135° for 7 hours. The cool mixture is triturated with hot water and treated with dilute ethanolic HCl to give the trihydrochloride of the title compound.

Quelle