Reaktion #349023

Reaktionsgleichung

2-(4-chlorophenyl)-3-methylbutanoyl chloride

α-trifluoromethyl-3-phenoxybenzyl alcohol

pyridine

→

α-trifluoromethyl-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutanoate

Ausbeute 98.3%

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThis compound was prepared in the manner of Example II
2. 2
   SonstigeVolatiles were removed from the crude
3. 3
   Sonstigereaction product at 100° C./0.02 mm
4. 4
   workup.DISTILLATIONthrough a short path Kugelrohr distillation system

Vorschrift

This compound was prepared in the manner of Example II, using 5.3 g of 2-(4-chlorophenyl)-3-methylbutanoyl chloride, whose preparation is described in Agr. Biol. Chem., 38, 881 (1974), together with J. Kagaku To Seibutsu, 14, 427 (1976), 4.6 g of α-trifluoromethyl-3-phenoxybenzyl alcohol, and 1.5 g of pyridine in 50 ml of toluene. Volatiles were removed from the crude reaction product at 100° C./0.02 mm through a short path Kugelrohr distillation system to give as a residue 7.8 g of α-trifluoromethyl-3-phenoxybenzyl 2-(4-chlorophenyl)-3-methylbutanoate. The ir spectrum was consistent with the assigned structure.

Quelle