Reaktion #347986

Reaktionsgleichung

2-methyl-3-nitrobenzoic acid

→

3-amino-2-methylbenzoic acid

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationwas filtered off through a bed of Celite® (50 g)
2. 2
   Sonstigethe solvent evaporated under reduced pressure

Vorschrift

A solution of 2-methyl-3-nitrobenzoic acid (mp. 182°-184° C., 22 g, 0.12 mol) in 400 mL of methanol was hydrogenated over platinum oxide (100 mg) for 45 minutes at 55 pounds per square inch (psi), whereupon the catalyst was filtered off through a bed of Celite® (50 g), and the solvent evaporated under reduced pressure to give 3-amino-2-methylbenzoic acid (mp. 178°-181° C.) in quantitative yield (18.3 g).

Quelle