Reaktion #346962

Reaktionsgleichung

Phenol

Methyl 5-formyl-2-hydroxy-3-(1-prop-2-enyl)benzoate

t-butyl bromoacetate

→

Methyl 5-formyl-2-(2-t-butyloxy-2-oxo-ethoxy)-3-(1-prop-2-enyl)benzoate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto give a yellow oil (quant.)

Vorschrift

Phenol 36b was alkylated with t-butyl bromoacetate the usual way to give a yellow oil (quant.). 1H-NMR (300 MHz, CDCl3): 9.94 (s, 1H), 8.21 (d, 1H, J=2 Hz), 7.90 (d, 1H, J=9 Hz), 6.05-5.92 (m, 1H), 5.15-5.05 (m, 2H), 4.51 (s, 2H), 3.93 (s, 3H), 3.61 (br d, 2H, J=7 Hz), 1.49 (s, 9H). Anal. Calc'd for C18H22O6 : C, 64.66; H, 6.63; Found: C, 64.54; H, 6.62.

Quelle