Reaktion #346944

Reaktionsgleichung

ε-caprolactone

chloromethyl phenyl sulphide

sodium metaperiodate

→

α-methylene-ε-caprolactone

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto give the sulphurized compound, which

Vorschrift

This synthesis was carried out by reaction of the silyl enol of ε-caprolactone with chloromethyl phenyl sulphide in the presence of a catalytic amount of zinc chloride to give the sulphurized compound, which was oxidized into sulphoxide using sodium metaperiodate. Pyrolysis of the sulphoxide in refluxing toluene gave α-methylene-ε-caprolactone.

Quelle