Reaktion #346843

Reaktionsgleichung

2-(aminoethoxy) ethanol

hexahydrophthalic anhydride

→

N-(2-hydroxyethoxyethyl)hexahydrophthalimide

Ausbeute 96.0%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeA 500-ml, two necked flask was equipped with a magnetic stirring bar
2. 2
   Temperaturheating mantle and condenser
3. 3
   workup.ADDITIONAfter the addition
4. 4
   Temperaturwas refluxed for 12 hours
5. 5
   SonstigeThe ethanol was removed with a rotoevaporator

Vorschrift

A 500-ml, two necked flask was equipped with a magnetic stirring bar, heating mantle and condenser. The flask was charged with 51 g of 2-(aminoethoxy) ethanol (0.49 mol.) and 250 ml of ethanol. Next, 75 g of hexahydrophthalic anhydride (0.49 mol.) was slowly added to the flask. After the addition was complete the reaction was refluxed for 12 hours. The IR spectrum indicated the reaction was complete. The ethanol was removed with a rotoevaporator to yield 113 g (96%) of N-(2-hydroxyethoxyethyl)hexahydrophthalimide.

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