Reaktion #346794

Reaktionsgleichung

3-allyl-4-hydroxy-benzaldehyde

sodium acetate

N-acetylglycine

acetic anhydride

→

2-Methyl-4-(4-acetoxy-3-allyl-benzylidene)-5-(4H)-oxazolone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstige2 hours
2. 2
   Sonstigethe crystals which have separated out
3. 3
   Filtrationare filtered off
4. 4
   Waschenwashed with water
5. 5
   Sonstigedried in a vacuum desiccator
6. 6
   Sonstigefinally recrystallised from carbon tetrachloride

Vorschrift

40.5 g (0.25 mol) of 3-allyl-4-hydroxy-benzaldehyde, 10.3 g of sodium acetate, 19.9 g of N-acetylglycine and 63.5 g of acetic anhydride are together heated for 30 minutes to 100° C. and then for 21/2 hours to the reflux temperature. The resulting solution is cooled to 0° C. and the crystals which have separated out are filtered off, washed with water, dried in a vacuum desiccator and finally recrystallised from carbon tetrachloride. 2-Methyl-4-(4-acetoxy-3-allyl-benzylidene)-5-(4H)-oxazolone of melting point 108°-109° C. is obtained.

Quelle