Reaktion #346511

Reaktionsgleichung

(+)-4,5,6,7-tetrahydrobenzo[b]thiophen-4-amine

(S)-(-)-N-benzoyl glutamic acid

→

(+)-4,5,6,7-tetrahydrobenzo[b]thien-4-ylurea

Reaktionsbedingungen

Vorschrift

Similarly, the salt of (+)-4,5,6,7-tetrahydrobenzo[b]thiophen-4-amine and (S)-(-)-N-benzoyl glutamic acid is treated in the above manner to afford (+)-4,5,6,7-tetrahydrobenzo[b]thien-4-ylurea, melting point 218° C. to 220° C.; [α]589 25 +60° , [α]436 +149.8° , [α]365 +272.5°.

Quelle