Reaktion #346236

Reaktionsgleichung

diketene

m-benzyloxy-aniline

→

m-benzyloxy-acetylacetanilide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigem-hydroxy-3-methoxy-crotonanilide of formula V may be prepared

Vorschrift

m-hydroxy-3-methoxy-crotonanilide of formula V may be prepared by reacting diketene with m-benzyloxy-aniline to form m-benzyloxy-acetylacetanilide which is then reacted with methyl orthoformate to form m-benzyloxy-3,3-dimethoxybutyranilide which is converted by hydrogenolysis into m-hydroxy 3,3-dimethoxy-butyranilide which is then heated. Other compounds of formula V may be made in an analogous fashion.

Quelle