Reaktion #345800

ord-a1a859e76bb84fc5aa7274d6ceb4c225

Reaktionsgleichung

CCCCCC(CCCN(CCCCCCC(=O)OCC)S(C)=O)OC(C)=O
ethyl 7-[N-(4-acetoxynonyl)methanesulfinamido]heptanoate
CCOC(=O)CCCCCCNS(C)(=O)=O
ethyl 7-(methanesulfonamido)heptanoate
CCOC(=O)CCCCCCNS(C)=O
ethyl 7-(methanesulfinamido)heptanoate
→
CCCCCC(/C=C/CN(CCCCCC(CC)C(=O)O)S(C)(=O)=O)OC(C)=O
7-[N-(4-hydroxynonyl)methanesulfinamido]heptanoic acid
CCCCCC(/C=C/CN(CCCCCC(CC)C(=O)O)S(C)(=O)=O)OC(C)=O
ethyl 7-[N-(4-acetoxy-(E)-2-nonenyl)methanesulfonamido]heptanoic acid

Edukte

CCCCCC(CCCN(CCCCCCC(=O)OCC)S(C)=O)OC(C)=O
ethyl 7-[N-(4-acetoxynonyl)methanesulfinamido]heptanoate
CCOC(=O)CCCCCCNS(C)(=O)=O
ethyl 7-(methanesulfonamido)heptanoate
CCOC(=O)CCCCCCNS(C)=O
ethyl 7-(methanesulfinamido)heptanoate
—
product

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe synthesis of this compound

Vorschrift

The synthesis of this compound is carried out as described in Example 1 except that, in Step A, the ethyl 7-(methanesulfonamido)heptanoate is replaced by an equimolar amount of ethyl 7-(methanesulfinamido)heptanoate (Example T). The product of Step A is thus ethyl 7-[N-(4-acetoxynonyl)methanesulfinamido]heptanoate. The subsequent step yields 7-[N-(4-hydroxynonyl)methanesulfinamido]heptanoic acid (B).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04033996uspto-grants-1977_07