Reaktion #345768

Reaktionsgleichung

methyl chloroformate

methyl chloroformate

cyclooctanol

pyridine

pyridine hydrochloride

→

Methyl cyclooctyl carbonate

Lösungsmittel

benzene

benzene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder external cooling at 0° to 5° C
2. 2
   Waschenwashed with diluted hydrochloric acid, sodium hydroxide solution and water
3. 3
   Sonstigedried
4. 4
   workup.DISTILLATIONAfter the solvent had been distilled off
5. 5
   workup.DISTILLATIONthe raw ester was distilled in vacuo by means of a Vigreux column
6. 6
   SonstigeA colorless liquid was obtained which

Vorschrift

18.9 gm of methyl chloroformate were added drop-by-drop under agitation to a solution of 25.6 gm of cyclooctanol and 15.8 gm of absolute pyridine in 150 ml of dry benzene under external cooling at 0° to 5° C. After the methyl chloroformate had been added, agitation was continued for 12 hours at room temperature. Then, the benzene phase was drawn off from the precipitated pyridine hydrochloride, and washed with diluted hydrochloric acid, sodium hydroxide solution and water, and dried. After the solvent had been distilled off, the raw ester was distilled in vacuo by means of a Vigreux column. A colorless liquid was obtained which had a herbal, very natural and complex fragrance which is distinguished by a strong and long-clinging flowery jasmine scent.

Quelle