Reaktion #344860

ord-bd28bc9a3f394ae3a460136e6323746f

Reaktionsgleichung

CCCCCCCCCCCC(=O)OC1CC(c2ccccc2)NC(c2ccccc2)C1C
2,6-diphenyl-3-methylpiperidin-4-yl laurate
CC1(C)OO1
dimethyldioxirane
→
CCCCCCCCCCCC(=O)OC1CC(c2ccccc2)N(O)C(c2ccccc2)C1C
title compound
Ausbeute 99.4%
CCCCCCCCCCCC(=O)OC1CC(c2ccccc2)N(O)C(c2ccccc2)C1C
1-Hydroxy-2,6-diphenyl-3-methylpiperidin-4-yl Laurate
Ausbeute 99.4%

Edukte

CCCCCCCCCCCC(=O)OC1CC(c2ccccc2)NC(c2ccccc2)C1C
2,6-diphenyl-3-methylpiperidin-4-yl laurate
CC1(C)OO1
dimethyldioxirane

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The general procedure of Example 2 is repeated using 11.5 g (25.5 mmol) of 2,6-diphenyl-3-methylpiperidin-4-yl laurate and 570 mL (25.5 mmol) of dimethyldioxirane (0.045M in acetone). 11.8 g (99% yield) of the title compound is isolated: mp 84°-91° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05262538uspto-grants-1993_11