Reaktion #343280

Reaktionsgleichung

4,8-dimethylbicyclo[3.3.1]nona-7-en-2-ol

acetic anhydride

pyridine

→

title compound

Ausbeute 87.0%

4,8-dimethylbicyclo[3.3.1]nona-7-en-2-yl acetate

Ausbeute 87.0%

Lösungsmittel

tetrahydrofuran

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe resulting mixture was heated
2. 2
   Temperaturunder reflux for 5 hours
3. 3
   TemperaturAfter cooling
4. 4
   workup.DISTILLATIONthe tetrahydrofuran was distilled off

Vorschrift

To a solution of 10 g (60.2 mmol) of 4,8-dimethylbicyclo[3.3.1]nona-7-en-2-ol [IA] in 40 ml of tetrahydrofuran were added 6.8 g (66.6 mmol) of acetic anhydride and 5.2 g (65.7 mmol) of pyridine and the resulting mixture was heated under reflux for 5 hours. After cooling, the tetrahydrofuran was distilled off, the residue was subjected to column chromatography and eluate with toluene gave 10.9 g of the title compound, which had a woody-like smell.

Quelle