Reaktion #343107

Reaktionsgleichung

o-methoxythiophenol

o-iodobenzoic acid

potassium hydroxide

→

title product

2-(o-Methoxyphenylthio) benzoic acid

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder reflux for 3 hours
2. 2
   FiltrationFilter the reaction mixture hot
3. 3
   Filtrationagain filter the filtrate through celite
4. 4
   SonstigeSeparate the precipitate
5. 5
   Waschenwash well with water
6. 6
   Sonstigedry in vacuo at 70° C.

Vorschrift

Stir under reflux for 3 hours a mixture of 70 g (0.5 mole) of o-methoxythiophenol, 120.5 g (0.486 mole) of o-iodobenzoic acid 81.7 g (1.46 mole) of potassium hydroxide, 85 g (1.34 mole) of copper powder and 800 ml of water. Filter the reaction mixture hot and again filter the filtrate through celite. Acidify the filtrate with concentrated hydrochloric acid. Separate the precipitate, wash well with water and dry in vacuo at 70° C. to obtain the title product. (m.p. 198°-200° C.).

Quelle