Reaktion #342269

Reaktionsgleichung

5-(2-bromoethoxy)-2,3-dihydro-benzo[1,4]dioxine

4,5-dimethyl-thiazol-2-ylamine

→

title compound

Ausbeute 13.0%

3-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-4,5-dimethyl-3H-thiazol-2-ylideneamine hydrobromide

Ausbeute 13.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe mixture was cooled to ambient temperature
2. 2
   Sonstigethe residue was recrystallized from ethanol

Vorschrift

A mixture of 5-(2-bromoethoxy)-2,3-dihydro-benzo[1,4]dioxine (1.2 g, 4.7 mmol) and 4,5-dimethyl-thiazol-2-ylamine (0.50 g, 3.9 mmol) was heated at 85° C. for 7 hours. The mixture was cooled to ambient temperature and the residue was recrystallized from ethanol to provide 0.18 g (13%) of the title compound.

Quelle