Reaktion #342161

Reaktionsgleichung

aniline

malononitrile

4-hydrazinobenzoic acid

2-(phenylhydrazono)malononitrile

→

4-(3,5-diamino-4-phenylazopyrazol-1-yl)benzoic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe resulting solid was isolated by filtration
2. 2
   Waschenwashed with ethanol
3. 3
   Sonstigedried

Vorschrift

4-(3,5-diamino-4-phenylazopyrazol-1-yl)benzoic acid was prepared using 85 mg (0.5 mmol) of 2-(phenylhydrazono)malononitrile, which was derived from aniline (10 mL, 107 mmol) and malononitrile (161 mmol), and 4-hydrazinobenzoic acid (76 mg, 0.5° mmol). After reacting for 4 hrs, the reaction remained as a slurry; however, analysis of the reaction solution by TLC indicated that no starting material remained. The resulting solid was isolated by filtration, washed with ethanol, and dried to yield 22 mg (14%) of the compound as a brown solid.

Quelle