Reaktion #341758

ord-b6420a1b26ec4dd8a45fae7515079680

Reaktionsgleichung

CCc1ccc(Cl)c(CC)c1CC1=NCCN1
2-(3-chloro-2,6-diethyl-benzyl)-4,5-dihydro-1H-imidazole
CCc1ccc(Cl)c(CC)c1CC1=NCCN1
2-(3-Chloro-2,6-diethyl-benzyl)-4,5-dihydro-1H-imidazole
O=c1n(Cl)c(=O)n(Cl)c(=O)n1Cl
TCCA
C1CCC2=NCCCN2CC1
DBU
CCc1ccc(Cl)c(CC)c1Cc1ncc[nH]1
2-(3-Chloro-2,6-diethyl-benzyl)-1H-imidazole

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2-(3-Chloro-2,6-diethyl-benzyl)-1H-imidazole was prepared from 2-(3-chloro-2,6-diethyl-benzyl)-4,5-dihydro-1H-imidazole (Example 196), TCCA and DBU in analogy to Example 194e): light yellow crystals; MS (ISP): 251.3 ([M+H]+, 39%), 249.2 ([M+H]+, 100%).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07875645B2uspto-grants-2011_01