Reaktion #341756

ord-951bd66296824c0f8af8e7958930c890

Reaktionsgleichung

CC(C)c1cccc(C(C)C)c1CC1=NCCN1
2-(2,6-diisopropyl-benzyl)-4,5-dihydro-1H-imidazole
CC(C)c1cccc(C(C)C)c1CC1=NCCN1
2-(2,6-Diisopropyl-benzyl)-4,5-dihydro-1H-imidazole
O=c1n(Cl)c(=O)n(Cl)c(=O)n1Cl
TCCA
C1CCC2=NCCCN2CC1
DBU
→
CC(C)c1cccc(C(C)C)c1Cc1ncc[nH]1
2-(2,6-Diisopropyl-benzyl)-1H-imidazole

Edukte

CC(C)c1cccc(C(C)C)c1CC1=NCCN1
2-(2,6-diisopropyl-benzyl)-4,5-dihydro-1H-imidazole
CC(C)c1cccc(C(C)C)c1CC1=NCCN1
2-(2,6-Diisopropyl-benzyl)-4,5-dihydro-1H-imidazole
O=c1n(Cl)c(=O)n(Cl)c(=O)n1Cl
TCCA
C1CCC2=NCCCN2CC1
DBU

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2-(2,6-Diisopropyl-benzyl)-1H-imidazole was prepared from 2-(2,6-diisopropyl-benzyl)-4,5-dihydro-1H-imidazole (Example 4), TCCA and DBU in analogy to Example 194e): yellow crystals; MS (ISP): 243.4 ([M+H]+).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07875645B2uspto-grants-2011_01