Reaktion #341316

Reaktionsgleichung

4-Bromophenol

potassium carbonate

benzyl bromide

→

4-benzyloxybromobenzene

Lösungsmittel

acetone

ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe reaction was refluxed under a nitrogen atmosphere
2. 2
   TemperaturAfter 5-6 hours reflux
3. 3
   WaschenThis solution was washed with water
4. 4
   Trocknendried over anhydrous magnesium sulfate
5. 5
   Sonstigeevaporated to dryness
6. 6
   SonstigeA white fluffy solid was obtained

Vorschrift

4-Bromophenol (2 g, 0.0116 mol) in acetone (40 mL) was treated with potassium carbonate anhydrous (1.91 g, 1.2 equivalents) and benzyl bromide (1.44 mL, 1.05 equivalents). The reaction was refluxed under a nitrogen atmosphere. After 5-6 hours reflux, the reaction was cooled to room temperature and diluted with an equal volume of ethyl acetate. This solution was washed with water, dried over anhydrous magnesium sulfate and evaporated to dryness. A white fluffy solid was obtained. Yield=2.36 g (73%).

Quelle