Reaktion #340219

Reaktionsgleichung

sodium nitrite

1H-indazol-4-ylamine

sodium tetrafluoroborate

→

1H-indazole-4-diazonium, tetrafluoroborate salt

Ausbeute 20.0%

Lösungsmittel

water

hydrochloric acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONwas added
2. 2
   Filtrationwas filtered
3. 3
   Waschenwashed briefly with water

Vorschrift

An aqueous solution of sodium nitrite (337 mg, 4.89 mmol) in water (2 mL) was added dropwise to a suspension of 1H-indazol-4-ylamine (631 mg, 4.74 mmol) in 6M hydrochloric acid (7.2 mL) at below 0° C. After stirring for 30 minutes sodium tetrafluoroborate (724 mg) was added. The reaction mixture became very thick and was filtered and washed briefly with water to yield 1H-indazole-4-diazonium, tetrafluoroborate salt (69) (218 mg, 20%) as a deep red solid.

Quelle