Reaktion #339899

Reaktionsgleichung

N-{5-[6-chloro-5-(2,4-dimethyl-1,3-thiazol-5-ylsulfonamido)pyridin-3-yl]-4-methyl-1,3-thiazol-2-yl}acetamide

hydrochloric acid

→

title compound

N-[5-(2-Amino-4-methyl-1,3-thiazol-5-yl)-2-chloropyridin-3-yl]-2,4-dimethyl-1,3-thiazole-5-sulfonamide

Reaktionsbedingungen

Vorschrift

Using an analogous procedure to that described in Example 61, N-{5-[6-chloro-5-(2,4-dimethyl-1,3-thiazol-5-ylsulfonamido)pyridin-3-yl]-4-methyl-1,3-thiazol-2-yl}acetamide was hydrolysed with aqueous hydrochloric acid solution to give the title compound; 1H NMR Spectrum: (DMSOd6) 2.18 (s, 3H), 2.35 (s, 3H), 2.61 (s, 3H), 7.30 (s, 2H), 7.64 (d, 11H), 8.22 (s, 1H), 10.80 (br s, 1H); Mass Spectrum: M+H+ 416.

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