Reaktion #339897

ord-c3ef592cb88a4dc694659e3a932bf2dd

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Using an analogous procedure to that described in Example 61, N-[5-(6-chloro-5-methylsulfonylaminopyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]acetamide was hydrolysed with aqueous hydrochloric acid solution to give the title compound; 1H NMR Spectrum: (DMSOd6) 2.22 (s, 3H); 3.13 (s, 3H); 7.23 (s, 2H); 7.76 (d, 1H); 8.21 (d, 1H); 8.79 (br s, 1H); Mass Spectrum: M+H+ 319.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07868188B2uspto-grants-2011_01