Reaktion #339612

Reaktionsgleichung

4-bromo-biphenyl

Chlorosulfonic acid

→

4′-bromo-biphenyl-4-sulfonic acid

Ausbeute 92.0%

Lösungsmittel

chloroform

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeA 500 mL round-bottom-flask equipped with an addition funnel
2. 2
   Sonstigethen purged with nitrogen
3. 3
   workup.STIRRINGthen stirred for 1 hour
4. 4
   FiltrationThe resulting precipitate was collected by vacuum filtration
5. 5
   Waschenwashed with cold chloroform
6. 6
   Sonstigedried under vacuum

Vorschrift

A 500 mL round-bottom-flask equipped with an addition funnel, stirring bar, and gas inlet was charged with 4-bromo-biphenyl (50 g, 0.215 mol) and chloroform (200 mL) then purged with nitrogen. Chlorosulfonic acid (18 mL, 0.27 mol) was added dropwise to the solution from the addition funnel then stirred for 1 hour. The resulting precipitate was collected by vacuum filtration, washed with cold chloroform, and dried under vacuum to give 61.97 g of 4′-bromo-biphenyl-4-sulfonic acid (92% yield).

Quelle