Reaktion #339447

Reaktionsgleichung

2-bromo-3-methylthiophene

2-fluoro-5-pyridine-boronic acid

→

desired compound

Ausbeute 75.9%

2-Fluoro-5-(3-methyl-thiophen-2-yl)-pyridine

Ausbeute 75.9%

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThis compound was prepared in analogy to Example 52

Vorschrift

This compound was prepared in analogy to Example 52, starting from 2-bromo-3-methylthiophene (2.6 g, 15 mmol) and 2-fluoro-5-pyridine-boronic acid (2.3 g, 16.5 mmol, 1.1 equiv.) to obtain 2.2 g of the desired compound as a light yellow oil. MS (ES): m/e 194.2 (M+H)

Quelle