Reaktion #338958

Reaktionsgleichung

2-(4-bromo-phenyl)-6-phenyl-imidazo [1,2-a] pyridine

10-naphthalen-2-yl-anthracene-9-boronic acid

sodium carbonate

→

yellowish white solids

Ausbeute 77.8%

2-[4-(10-naphthalen-2-yl-anthracen-9-yl)-phenyl]-6-phenyl-imidazo [1,2-a] pyridine

Ausbeute 77.8%

Lösungsmittel

1,2-dimethoxyethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder heating for 7 hours
2. 2
   SonstigeAfter completion of the reaction, separation
3. 3
   Filtrationwith filtration
4. 4
   Waschenresultant crystals were washed with water and methanol

Vorschrift

Dissolving 4.0 g (11 mmol) of 2-(4-bromo-phenyl)-6-phenyl-imidazo [1,2-a] pyridine, 4.0 g (11 mmol) of 10-naphthalen-2-yl-anthracene-9-boronic acid and 0.27 g of tetrakis (triphenylphosphine) palladium into 40 milliliter of 1,2-dimethoxyethane, adding 18 milliliter of 2.0M sodium carbonate aqueous solution, the resultant suspension was refluxed under heating for 7 hours. After completion of the reaction, separation with filtration was carried out and resultant crystals were washed with water and methanol, thereby obtaining 4.9 g of yellowish white solids (yield: 76%). As a result of mass spectrum (MS) analysis, it was recognized that m/e=572 for molecular weight of 572.23 and the yellowish white solids were identified as the aimed substance.

Quelle