Reaktion #336399

Reaktionsgleichung

heptanohydrazide

7-octyl-2-fluorenecarbonyl chloride

pyridine

→

N-heptanoyl-N'-(7-octyl-2-fluorenecarbonyl) hydrazine

Ausbeute 69.8%

Lösungsmittel

dioxane

dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.STIRRINGfurther stirring for 30 minutes at 85°-88° C
2. 2
   SonstigeAfter the reaction
3. 3
   Temperaturthe reaction mixture was cooled
4. 4
   Sonstigeto precipitate a crystal
5. 5
   SonstigeThe crystal was recrystallized from a mixture solvent of toluene-acetone

Vorschrift

Then, in a 50 ml-three-necked flask, 0.32 g (2.22 mM) of heptanohydrazide and 15 ml of dioxane were placed. To the mixture, a solution of the above-prepared 7-octyl-2-fluorenecarbonyl chloride in 5 ml of dioxane was added, followed by addition of 0.84 ml of pyridine at about 85° C. under stirring and further stirring for 30 minutes at 85°-88° C. After the reaction, the reaction mixture was cooled and poured into 200 ml of ice water to precipitate a crystal. The crystal was recrystallized from a mixture solvent of toluene-acetone to obtain 0.68 g of N-heptanoyl-N'-(7-octyl-2-fluorenecarbonyl) hydrazine (Yield: 69.8%).

Quelle