Reaktion #3357

ord-22175d52cf8d4bbdad038a1e70ab65ca

Reaktionsgleichung

NCCCC(=O)O
4-amino-butanoic acid
O=C(Cl)c1ccccc1SSc1ccccc1C(=O)Cl
2,2'-dithiobisbenzoyl chloride
→
O=C(O)CCCNC(=O)c1ccccc1SSc1ccccc1C(=O)NCCCC(=O)O
title compound
Ausbeute 49.9%
O=C(O)CCCNC(=O)c1ccccc1SSc1ccccc1C(=O)NCCCC(=O)O
4-[2-[2-(3-Carboxypropylcarbamoyl)phenyldisulfanyl]benzoylamino] butanoic acid
Ausbeute 49.9%

Edukte

NCCCC(=O)O
4-amino-butanoic acid
O=C(Cl)c1ccccc1SSc1ccccc1C(=O)Cl
2,2'-dithiobisbenzoyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following the procedure in Preparation 30, 16 g (0.15 mol) of 4-amino-butanoic acid was reacted with 10.8 g (0.03 mol) of 2,2'-dithiobisbenzoyl chloride to afford 7.14 g of the title compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05733921uspto-grants-1998_03