Reaktion #335320

Reaktionsgleichung

1-hexadecanol

2-[(acetyloxy)methyl]-2-propenoic acid, ethyl ester

dimethylaminopyridine

→

desired compound

Ausbeute 39.3%

(Hexadecyloxylmethyl]-2-propenoic acid, ethyl ester

Ausbeute 39.3%

Lösungsmittel

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe solvent is evaporated

Vorschrift

To a mixture of 1.1 g of 1-hexadecanol and 400 mg of 2-[(acetyloxy)methyl]-2-propenoic acid, ethyl ester in 15 ml of dichloromethane is added 550 mg of dimethylaminopyridine. This mixture is stirred overnight, then the solvent is evaporated and the residue subjected to preparative tlc (25% ethyl acetate/petroleum ether), to give 324 mg of the desired compound.

Quelle