Reaktion #3345

Reaktionsgleichung

3-dimethylaminobenzylchloride hydrochloride

5,5-dimethyl-2,4-dithiohydantoin

sodium methoxide

→

desired compound

2,4-bis-(3-dimethylaminobenzylthio)-5,5-dimethyl-5H-imidazole

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONThe reaction mixture was treated
2. 2
   Sonstigepurified by column chromatograph (CHCl3)

Vorschrift

Initially, 3.1 g of 3-dimethylaminobenzylchloride hydrochloride was added to a mixture of 0.8 g of 5,5-dimethyl-2,4-dithiohydantoin and 1.34 g of sodium methoxide in 50 mL of methanol (MeOH). The reaction mixture was treated following the procedure used in Example 56, and purified by column chromatograph (CHCl3) to give the desired compound in the form of a syrup. The yield of this compound was 1.65 g with a yield ratio of 82.9%.

Quelle